abstract：:Wildlife biologists often use grid-based designs to sample animals and generate abundance estimates. Although sampling in grids is theoretically sound, in application, the method can be logistically difficult and expensive when sampling elusive species inhabiting extensive areas. These factors make it challenging to s...

journal_title：PeerJ

authors： Harris G,Farley S,Russell GJ,Butler MJ,Selinger J

更新日期：2013-12-17 00:00:00

abstract：:Prostaglandin E1 (PGE1), known pharmaceutically as alprostadil, has vasodilatory properties and is used widely in various clinical settings. In addition to acute vasodilatory properties, PGE1 may exert beneficial effects by altering protein expression of vascular cells. PGE1 is reported to be a potent stimulator of an...

journal_title：PeerJ

authors： Suzuki K,Nishi K,Takabuchi S,Kai S,Matsuyama T,Kurosawa S,Adachi T,Maruyama T,Fukuda K,Hirota K

更新日期：2013-11-28 00:00:00

abstract：:Ocean acidification threatens the foundation of tropical coral reefs. This study investigated three aspects of ocean acidification: (i) the rates at which perforate and imperforate coral-colony skeletons passively dissolve when pH is 7.8, which is predicted to occur globally by 2100, (ii) the rates of passive dissolut...

journal_title：PeerJ

authors： van Woesik R,van Woesik K,van Woesik L,van Woesik S

更新日期：2013-11-21 00:00:00

abstract：:Helminths include both parasitic nematodes (roundworms) and platyhelminths (trematode and cestode flatworms) that are abundant, and are of clinical importance. The genetic characterization of parasitic flatworms using advanced molecular tools is central to the diagnosis and control of infections. Although the nuclear ...

journal_title：PeerJ

authors： Biswal DK,Ghatani S,Shylla JA,Sahu R,Mullapudi N,Bhattacharya A,Tandon V

更新日期：2013-11-12 00:00:00

abstract：:Cold-water corals provide an important habitat for a rich fauna along the continental margins and slopes. Although these azooxanthellate corals are considered particularly sensitive to ocean acidification, their responses to natural variations in pH and aragonite saturation are largely unknown due to the difficulty of...

journal_title：PeerJ

authors： Fillinger L,Richter C

更新日期：2013-10-29 00:00:00

abstract：:We developed a novel method based on the Fourier analysis of protein molecular surfaces to speed up the analysis of the vast structural data generated in the post-genomic era. This method computes the power spectrum of surfaces of the molecular electrostatic potential, whose three-dimensional coordinates have been eit...

journal_title：PeerJ

authors： Carvalho CS,Vlachakis D,Tsiliki G,Megalooikonomou V,Kossida S

更新日期：2013-10-22 00:00:00

abstract：:Background. In recent years, there has been an explosion in the number of technical and medical diagnostic platforms being developed. This has greatly improved our ability to more accurately, and more comprehensively, explore and characterize human biological systems on the individual level. Large quantities of biomed...

journal_title：PeerJ

authors： O'Rawe JA,Fang H,Rynearson S,Robison R,Kiruluta ES,Higgins G,Eilbeck K,Reese MG,Lyon GJ

更新日期：2013-10-03 00:00:00

abstract：:We provided chimpanzees (Pan troglodytes) with the ability to improve the quality of food rewards they received in a dyadic test of inequity. We were interested to see if this provision influenced their responses and, if so, whether it was mediated by a social partner's outcomes. We tested eight dyads using an exchang...

journal_title：PeerJ

authors： Hopper LM,Lambeth SP,Schapiro SJ,Brosnan SF

更新日期：2013-09-17 00:00:00

abstract：:NA-glycine is an endogenous lipid molecule with analgesic properties, which is structurally similar to the endocannabinoids 2-AG and anandamide but does not interact with cannabinoid receptors. NA-glycine has been suggested to act at the G-protein coupled receptors GPR18 and GPR92. Recently, we have described that NA-...

journal_title：PeerJ

authors： Baur R,Gertsch J,Sigel E

更新日期：2013-09-10 00:00:00

abstract：:Dorsal horn neurons in the spinal cord integrate and relay sensory information to higher brain centers. These neurons are organized in specific laminae and different transcription factors are involved in their specification. The murine homeodomain Gbx1 protein is expressed in the mantle zone of the spinal cord at E12....

journal_title：PeerJ

authors： Meziane H,Fraulob V,Riet F,Krezel W,Selloum M,Geffarth M,Acampora D,Hérault Y,Simeone A,Brand M,Dollé P,Rhinn M

更新日期：2013-08-29 00:00:00

abstract：:Introduction. Adolescent interpersonal violence is a global public health problem, yet gaps remain in the epidemiologic literature on adolescent violence in low- and middle-income countries (LMIC). Prevalence rates and risk and protective factors reported in high-income countries may be different from those reported i...

journal_title：PeerJ

authors： Celedonia KL,Wilson ML,El Gammal HA,Hagras AM

更新日期：2013-08-13 00:00:00

abstract：:Background. The relative efficacy and safety of lacosamide as adjunctive therapy compared to other antiepileptic drugs has not been well established. Objective. To determine if lacosamide provides improved efficacy and safety, reduced length of hospital stay and improved quality of life compared with other anti-epilep...

journal_title：PeerJ

authors： Sawh SC,Newman JJ,Deshpande S,Jones PM

更新日期：2013-08-06 00:00:00

abstract：:We present a semi-empirical (PM6-based) computational method for systematically estimating the effect of all possible single mutants, within a certain radius of the active site, on the barrier height of an enzymatic reaction. The intent of this method is not a quantitative prediction of the barrier heights, but rather...

journal_title：PeerJ

authors： Hediger MR,Steinmann C,De Vico L,Jensen JH

更新日期：2013-07-23 00:00:00

abstract：:Recent upperward migration of plants and animals along altitudinal gradients and poleward movement of animal range boundaries have been confirmed by many studies. This phenomenon is considered to be part of the fingerprint of recent climate change on the biosphere. Here I examine whether poleward movement is occurring...

journal_title：PeerJ

authors： Groom QJ

更新日期：2013-05-28 00:00:00

abstract：:The currently-accepted dogma when analysing human Alu transposable elements is that 'young' Alu elements are found in low GC regions and 'old' Alus in high GC regions. The correlation between high GC regions and high gene frequency regions make this observation particularly difficult to explain. Although a number of s...

journal_title：PeerJ

authors： Hellen EH,Brookfield JF

更新日期：2013-05-21 00:00:00

abstract：:The knowledge on the spatial distribution of soil available water capacity at a regional or national extent is essential, as soil water capacity is a component of the water and energy balances in the terrestrial ecosystem. It controls the evapotranspiration rate, and has a major impact on climate. This paper demonstra...

journal_title：PeerJ

authors： Hong SY,Minasny B,Han KH,Kim Y,Lee K

更新日期：2013-04-23 00:00:00

abstract：:'Living fossils', a phrase first coined by Darwin, are defined as species with limited recent diversification and high morphological stasis over long periods of evolutionary time. Morphological stasis, however, can potentially lead to diversification rates being underestimated. Notostraca, or tadpole shrimps, is an an...

journal_title：PeerJ

authors： Mathers TC,Hammond RL,Jenner RA,Hänfling B,Gómez A

更新日期：2013-04-02 00:00:00

abstract：:Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims of this study were to determine the prevalence of the combined morbidity of DM & hypothyroidism and whether...

journal_title：PeerJ

authors： Tirosh D,Benshalom-Tirosh N,Novack L,Press F,Beer-Weisel R,Wiznitzer A,Mazor M,Erez O

更新日期：2013-03-19 00:00:00

abstract：:Background. The age at which most young people are in tertiary education is also the age of peak onset for mental illness. Because mental health problems can have adverse effects on students' academic performance and welfare, institutions require guidance how they can best provide support. However, the scientific evid...

journal_title：PeerJ

authors： Reavley NJ,Ross AM,Killackey E,Jorm AF

更新日期：2013-02-26 00:00:00

abstract：:The recent publication of a number of high resolution bacterial voltage-gated sodium channel structures has opened the door for the mechanisms employed by these channels to distinguish between ions to be elucidated. The way these channels select between Na(+) and K(+) has been investigated in computational studies, bu...

journal_title：PeerJ

authors： Corry B

更新日期：2013-02-12 00:00:00

abstract：:Background. Caesarean birth rates in North America continue to rise, in the absence of benefit for mothers and babies. One reason may be that hospitalized labouring women spend most of their labours in recumbent or semi-recumbent positions. Although hands-and-knees position has theoretical advantages, efforts to encou...

journal_title：PeerJ

authors： Hodnett ED,Stremler R,Halpern SH,Weston J,Windrim R

更新日期：2013-02-12 00:00:00

abstract：:Pseudomonas syringae is the most widespread bacterial pathogen in plants. Several strains of P. syringae produce a phytotoxin, coronatine (COR), which acts as a jasmonic acid mimic and inhibits plant defense responses and contributes to disease symptom development. In this study, we found that COR inhibits early defen...

journal_title：PeerJ

authors： Lee S,Ishiga Y,Clermont K,Mysore KS

更新日期：2013-02-12 00:00:00